Krazy Kat debuted as a spinoff from The Dingbat Family, which it would supplant.
The United States broke diplomatic relations with Colombia over an ongoing dispute about the US's role in severing Panama in 1903 from the country, which was a fairly stinky thing for the US to do. It was based on our desire to see the canal built on the Isthmus of Panama. The US was attempting to repair the situation, which understandably upset Colombia.
The ongoing balkanization of Central America is a major source of its ongoing difficulties today. Some of the territory which is now in independent states bordering Mexico should really be part of Mexico and the balance, perhaps absent Panama, one single state. This would, in fact, comport with the original hopes of those who severed those regions from Spain.
The Interstate Commerce Commission ordered an investigation of all express train companies in the United States.
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